• Francesco Corradi, Lorenzo Ball, Claudia Brusasco, Anna Maria Riccio, Michele Baroffio, Giulio Bovio, Paolo Pelosi, and Vito Brusasco.
• Dipartimento Cardio-Nefro-Polmonare, Azienda Ospedaliera Universitaria di Parma, 43126 Parma, Italy.
• Respir Physiol Neurobiol. 2013 Jul 1; 187 (3): 244-9.

AbstractLung ultrasonography (LUS) and computed tomography (CT) were compared for quantitative assessment of extravascular lung water (EVLW) in 10 isolated bovine lung lobes. LUS and CT were obtained at different inflation pressures before and after instillation with known amounts of hypotonic saline. A video-based quantitative LUS analysis was superior to both single-frame quantitative analysis and visual scoring in the assessment of EVLW. Video-based mean LUS intensity was strongly correlated with EVLW density (r(2)=0.87) but weakly correlated with mean CT attenuation (r(2)=0.49) and physical density (r(2)=0.49). Mean CT attenuation was weakly correlated with EVLW density (r(2)=0.62) but strongly correlated with physical density (r(2)=0.99). When the effect of physical density was removed by partial correlation analysis, EVLW density was significantly correlated with video-based LUS intensity (r(2)=0.75) but not mean CT attenuation (r(2)=0.007). In conclusion, these findings suggest that quantitative LUS by video gray-scale analysis can assess EVLW more reliably than LUS visual scoring or quantitative CT.Copyright © 2013 Elsevier B.V. All rights reserved.

18 keywords...

hide…