• Mycoses · Dec 2011

    Case Reports

    Successful treatment of disseminated fusariosis with voriconazole in an acute lymphoblastic leukaemia patient.

    • Aurelie Labois, Christian Gray, and Stephane Lepretre.
    • Centre de Lutte contre le cancer Henri Becquerel, Rouen, France.
    • Mycoses. 2011 Dec 1; 54 Suppl 4: 8-11.

    AbstractFusarium species are actually the second most common pathogenic mould in immunocompromised patients, and it is difficult to treat such fusarial infections with current antifungal agents. We report the case of a 53-year-old woman with Philadelphia-positive acute lymphoblastic leukaemia. During induction chemotherapy with febrile neutropenia, she developed a disseminated fusariosis, with persistent fever refractory to antibacterial agents and caspofungin (as empirical therapy), painful skin lesions and respiratory impairment. Fusarium solani was isolated from skin biopsy. Voriconazole was successfully implemented as antifungal curative therapy. During the second intensive chemotherapy no reactivation of fusariosis was detected.© 2011 Blackwell Verlag GmbH.

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