• Vet. Clin. North Am. Equine Pract. · Aug 2014

    Review

    Update on the management of neonatal sepsis in horses.

    • Jon Palmer.
    • Graham French Neonatal Section, Connelly Intensive Care Unit, New Bolton Center, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USA. Electronic address: jepalmer@vet.upenn.edu.
    • Vet. Clin. North Am. Equine Pract. 2014 Aug 1; 30 (2): 317-36, vii.

    AbstractDespite advances in neonatal intensive care sepsis, severe sepsis and septic shock remain the biggest killers of neonatal foals. Management of this severe syndrome remains difficult, requiring intensive intervention. Key aspects of management include infection control, hemodynamic support, immunomodulatory interventions, and metabolic/endocrine support. Infection control largely consists of early antimicrobial therapy, plasma transfusions, and local therapy for the infected focus. In cases with severe sepsis or septic shock, hemodynamic support with fluids, vasoactive agents, and respiratory support insuring oxygen delivery to vital organs is important. Nutritional support is important, but close monitoring is needed to avoid hyperglycemia and hypoglycemia.Copyright © 2014 Elsevier Inc. All rights reserved.

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