• Br J Anaesth · Jul 1998

    Review

    Remifentanil and tramadol.

    • D J Duthie.
    • Department of Anaesthesia, University of Leicester, Glenfield Hospital.
    • Br J Anaesth. 1998 Jul 1; 81 (1): 51-7.

    AbstractThe lack of analgesic efficacy limits tramadol as a sole agent to treat severe pain after surgery. However, it has a relative lack of respiratory depressant and constipating effects compared with morphine and codeine, and does not share the propensity of nonsteroidal anti-inflammatory drugs to provoke asthma, gastrointestinal mucosal damage and renal impairment. It may well have a place in the management of pain after surgery, in combination with another drug, such as paracetamol, or after control of the worst of pain after surgery by a regional local anaesthetic technique.

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