• Clinics in chest medicine · Mar 2005

    Review

    Acute lung injury and bacterial infection.

    • Didier Dreyfuss and Jean-Damien Ricard.
    • Service de Réanimation Médicale, Hôpital Louis Mourier, Assistance Publique--Hôpitaux de Paris, Colombes 92700, France. didier.dreyfuss@lmr.ap.hop-paris.fr
    • Clin. Chest Med. 2005 Mar 1; 26 (1): 105-12.

    AbstractThe relationships between acute lung injury and bacterial infection are complex. Indeed, sepsis and in particular pneumonia are leading causes of acute lung injury. Bacterial superinfection of the lung is a frequent complication of acute lung injury. Because of impaired host defenses and prolonged mechanical ventilation, more than one third of patients with the acute respiratory distress syndrome acquire ventilator-associated pneumonia, with resistant pathogens in most instances. This complication is responsible for more than a doubling of the time on mechanical ventilation but does not seem to increase mortality.

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