• J. Pediatr. Surg. · Sep 2011

    Comparative Study

    Effectiveness of Biobrane for treatment of partial-thickness burns in children.

    • Aaron P Lesher, Ryan H Curry, Jill Evans, Valerie A Smith, Michael T Fitzgerald, Robert A Cina, Christian J Streck, and Andre V Hebra.
    • Division of Pediatric Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC 29425-6130, USA.
    • J. Pediatr. Surg. 2011 Sep 1; 46 (9): 1759-63.

    PurposeWound care for partial-thickness burns should alleviate pain, decrease hospital length of stay, and be readily applied to a variety of wounds. The effectiveness of Biobrane (UDL Laboratories, Rockford, IL) is compared with that of Beta Glucan Collagen (BGC; Brennan Medical, St. Paul, MN) in a retrospective cohort study.MethodsA retrospective chart review of all children treated at a tertiary care pediatric hospital between 2003 and 2009 identified patients with partial-thickness burns treated with Biobrane. These patients were compared with historical controls treated with BGC.ResultsA total of 235 children between the ages of 4 weeks and 18 years with an average of 6.0% body surface area partial-thickness burns were treated with Biobrane. In a multivariate statistical analysis, patients treated with Biobrane healed significantly faster than those treated with BGC (Biobrane vs BGC: median, 9 vs 13 days; P = .019; hazard ratio, 1.68). In addition, patients who required inpatient treatment trended toward having shorter length of hospital stay in the Biobrane group (2.6 vs 4.1 days, P = .079).ConclusionPartial-thickness burn care consists of early debridement and application of a burn wound dressing. Biobrane dressings result in faster healing compared with BGC and may decrease hospital length of stay for patients requiring inpatient admission.Copyright © 2011 Elsevier Inc. All rights reserved.

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