• J. Gastrointest. Surg. · Oct 2011

    Analysis of risk factors for delayed gastric emptying (DGE) after 387 pancreaticoduodenectomies with usage of 70 stapled reconstructions.

    • Yoshihiro Sakamoto, Yusuke Yamamoto, Shojiro Hata, Satoshi Nara, Minoru Esaki, Tsuyoshi Sano, Kazuaki Shimada, and Tomoo Kosuge.
    • National Cancer Center Hospital, Tokyo, Japan. yosakamo-tky@umin.ac.j.p
    • J. Gastrointest. Surg. 2011 Oct 1; 15 (10): 1789-97.

    BackgroundDelayed gastric emptying (DGE) is one of the most troublesome complications after pancreaticoduodenectomy (PD).MethodsBetween 2004 and 2009, 387 patients underwent PD and of these, 302 patients (78%) underwent pylorus-preserving PD. The stapled reconstruction of duodeno- or gastrojejunostomy was introduced in 2006, and 70 patients (18%) underwent stapled Roux-en-Y reconstruction. Postoperative DGE was defined based on the International Study Group on Pancreatic Surgery classification, and grade B or C DGE was considered to be clinically relevant. Risk factors for DGE were evaluated using univariate and multivariate analyses.ResultsFour patients died in the hospital (1.0%). Postoperative DGE was found in 70 patients (18%). DGE was less frequently seen in stapled reconstruction than in hand-sewn reconstruction (7.2% vs. 21%, P < 0.001), and in single-layer anastomosis than in double-layer anastomosis (12% vs. 24%, P = 0.02). The multivariate logistic regression analysis revealed that the independent risk factors for DGE were postoperative pancreatic fistula (risk ratio [RR] 2.4, P = 0.002), hand-sewn reconstruction (RR 2.9, P = 0.03) and male (RR 2.2, P = 0.02).ConclusionThe method of alimentary reconstruction affected the occurrence of DGE. The incidence of DGE was less in stapled reconstruction than in hand-sewn reconstruction.

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