• Mitchell I Clionsky and Emilymarie Clionsky.
• Clionsky Neuro Systems, Springfield, MA, USA. mitch@cns-neuro.com
• Am J Alzheimers Dis Other Demen. 2010 Dec 1; 25 (8): 650-6.

ObjectivesAccurate, economical identification of cognitive impairment would increase dementia detection and improve care of older patients.DesignAnalysis of archival neuropsychological data combined 3-word recall, time orientation, list memory, and clock drawing into the Memory Orientation Screening Test (MOST ™). The MOST was compared with Folstein Mini Mental State Examination (MMSE) and Mini-Cog to detect dementia presence and severity, and convergence with standardized neuropsychological tests. Internal consistency, retest reliabilities, completion likelihood, and time costs were calculated.ResultsThe MOST was significantly more sensitive than MMSE or Mini-Cog, twice as accurate as MMSE for identifying mild dementia, better correlated with standardized memory tests, more reliable over time, and minimally related to depression.ConclusionsThe MOST is routinely administered in less than 5 minutes by a medical assistant, more accurately identifies dementia and severity than current screening tests, and emulates longer memory testing, making it valuable for Annual Wellness Visits and many applied clinical settings.

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