-
Randomized Controlled Trial Clinical Trial
[Laryngeal edema after extubation. Do corticosteroids play a role in its prevention?].
- P Gaussorgues, F Boyer, D Piperno, M Gérard, P Léger, and D Robert.
- Service de Réanimation médicale, Hôpital de la Croix, Rousse, Lyon.
- Presse Med. 1987 Sep 26; 16 (31): 1531-2.
AbstractThe role of corticosteroids in the prevention of post-extubation laryngeal oedema was evaluated in a randomized study of 276 patients under mechanical ventilation. Fifty per cent of the patients received methylprednisolone 40 mg intramuscularly and intravenously. The nasotracheal tubes used had a large volume, low-pressure balloon. Laryngeal oedema, confirmed by laryngoscopy, occurred in six patients (2%), 4 of whom were in the corticosteroid-treated group, and required immediate reintubation in 4 cases. Thus, the incidence of laryngeal oedema was not modified by corticosteroids. Regular prescription of corticosteroids does not seem to be useful before extubation of patients intubated with large volume, low-pressure balloon tubes.
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