• Plos One · Jan 2013

    Comparative Study

    Reliability of FEV1/FEV6 to diagnose airflow obstruction compared with FEV1/FVC: the PLATINO longitudinal study.

    • Rogelio Perez-Padilla, Fernando C Wehrmeister, Bartolome R Celli, Maria Victorina Lopez-Varela, Maria Montes de Oca, Adriana Muiño, Carlos Talamo, Jose R Jardim, Gonzalo Valdivia, Carmen Lisboa, Ana Maria B Menezes, and PLATINO Team.
    • National Institute of Respiratory Diseases (INER), Mexico City, Mexico. perezpad@gmail.com
    • Plos One. 2013 Jan 1; 8 (8): e67960.

    QuestionA 6-second spirometry test is easier than full exhalations. We compared the reliability of the ratio of the Forced expiratory volume in 1 second/Forced expiratory volume in 6 seconds (FEV1/FEV6) to the ratio of the FEV1/Forced vital capacity (FEV1/FVC) for the detection of airway obstruction.MethodsThe PLATINO population-based survey in individuals aged 40 years and over designed to estimate the prevalence of post-Bronchodilator airway obstruction repeated for the same study participants after 5-9 years in three Latin-American cities.ResultsUsing the FEV1/FVCConclusionThe FEV1/FEV6 is a more reliable index than FEV1/FVC because FVC varies with the duration of the forced exhalation. Reporting FET and FEV1/FEV6

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