• Otolaryngol Head Neck Surg · Nov 2013

    Randomized Controlled Trial Comparative Study

    Topical levobupivacaine efficacy in pain control after functional endoscopic sinus surgery.

    • Süleyman Yilmaz, Sahnur Yildizbas, Ender Güçlü, Hüseyin Yaman, and Gülbin Yalçin Sezen.
    • Düzce Medical Faculty ENT Department, Düzce, Turkey.
    • Otolaryngol Head Neck Surg. 2013 Nov 1; 149 (5): 777-81.

    ObjectiveThe aim of this study was to find out the efficacy of a polyvinyl alcohol (PVA) sponge (Merocel Kennedy; Medtronic Xomed, Jacksonville, Florida) sinus pack soaked with levobupivacaine hydrochloride to control postoperative pain and analgesic need following functional endoscopic sinus surgery (FESS).Study DesignThe study was designed as a prospective, double-blind, randomized, controlled study. Forty-one patients who underwent FESS were included in the analysis. Setting A tertiary referral hospital in Turkey.Materials And MethodsPatients who underwent FESS were divided into 2 groups. The PVA sponge sinus packs were soaked with 5 mL of levobupivacaine hydrochloride (chirocaine 25 mg/10 mL; Abbott, Nycomed Pharma AS, Elverum, Norway) in group I and with 5 mL of saline in group II.Main Outcome MeasuresPostoperative pain levels were recorded using a visual analog scale (VAS score, 0-100) at 30 minutes and 1, 2, 8, 12, and 24 hours.ResultsThere were no statistically significant differences between groups regarding age, sex, and American Society of Anesthesiologists status. Postoperative VAS values at 30 minutes and 1, 2, 8, 12, and 24 hours were significantly lower in group I than in group II (P < .05). Supplemental analgesia amount was significantly lower in group I than in group II (P = .003).ConclusionUsing levobupivacaine-soaked PVA sponge sinus packs after FESS is an effective, easy, and quick method to control postoperative pain, and it improves patient comfort and tolerability.

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