• Annales de pédiatrie · Jan 1993

    Review Case Reports

    [Ischemic cerebrovascular accidents in homozygous sickle cell anemia. Two case reports].

    • E Mbonda, I Thuret, and N Pinsard.
    • Département de Pédiatrie, Centre Universitaire des Sciences de la Santé, Yaounde, Cameroun.
    • Ann Pediatr (Paris). 1993 Jan 1; 40 (1): 23-7.

    AbstractTwo cases of ischemic stroke in children of Tunisian descent with sickle cell anemia are reported. Patients were aged 3 years and 14 years, respectively. Periodic partial exchange transfusions with sedimented red blood cells of identical phenotype prevented further episodes of ischemic stroke. Transplantation of HLA-identical bone marrow from a family member offers a chance of complete cure of the hemoglobin disorder in these children who are at risk of recurrent stroke.

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