• A A Polupan, A S Goriachev, I A Savin, O E Satishur, A V Oshorov, K A Popugaev, A A Sychev, T F Tabasaranskiĭ, K Iu Krylov, E Iu Sokolova, O Iu Mezentseva, and V V Podlepich.
• Anesteziol Reanimatol. 2011 Jul 1 (4): 42-5.

AbstractThe study gives data on how to improve the way from mechanical to spontaneous breathing in patients with weakened respiratory drive after posterior fossa tumor removal. We compared the effectiveness of two methods of weaning from mechanical ventilation in these patients. The main group consisted of 6 patients weaned from ventilator with ASV mode. The control group was made up of 10 patients weaned from ventilator with SIMV or PS modes. The duration of weaning from ventilator using ASV mode was significantly shorter than with SIMV or PS modes. During ASV ventilation spontaneous breath rate gradually increased. In all patients the level of P0,1 index representing respiratory center activity was initially lower than normal. While spontaneous breath activity increased the level of P0,1 index also gradually normalized. Plmax index (respiratory effort index) measured once a day increased as well. Weakened respiratory drive is accompanied by P0,1 and Plmax indexes' decrease in patients after posterior fossa tumor removal. ASV mode in these patients allows quicker weaning from mechanical ventilation.

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