• M Kamenik, V Paver-Erzen, L Tos, Z Zabavnik, N Krcevski-Skvarc, and I Horvat.
• Abteilung für Anesthesiologie, Intensivtherapie und Schmerztherapie, Lehrkrankenhaus Maribor, Slowenien. mirt.kamenik@mf.uni-lj.si
• Anaesthesist. 2000 Jun 1; 49 (6): 517-22.

BackgroundOur study compared the haemodynamic changes after spinal anesthesia with 2% lignocaine and 0.5% plain bupivacaine.MethodsA controlled, randomized trial was performed on 30 patients scheduled for arthroscopic knee surgery. 2% lignocaine and 0.5% plain bupivacaine were used for spinal anaesthesia. We measured cardiac output (electrical bioimpedance cardiography), blood pressure and development of sensory blockade before and for 25 minutes after spinal anaesthesia.ResultsIn patients developing a sensory block below T6 there were no differences between both anaesthetics in haemodynamic parameters. But in patients developing a sensory block at or above T6 there was a greater drop in mean arterial pressure and cardiac output and a faster decrease in heart rate for bupivacaine compared to patients receiving Lignocaine.ConclusionIn patients developing a sensory block at or above the T6 dermatome, the decrease in cardiac output and mean arterial pressure in the first 25 min after spinal anaesthesia is smaller when 2% lignocaine rather than 0.5% bupivacaine is used for blockade.

26 keywords...

hide…