• J Clin Ultrasound · Sep 2007

    Case Reports

    Splenic focal lesions as manifestation of sarcoidosis: Characterization with contrast-enhanced sonography.

    • María José Pérez-Grueso, Alejandro Repiso, Rafael Gómez, Concepción Gonzalez, Tomás de Artaza, Julio Valle, Almudena García, and Jose María Carrobles.
    • Department of Gastroenterology, Virgen de la Salud Hospital, Avda Barber no. 30, Toledo 45004, Spain.
    • J Clin Ultrasound. 2007 Sep 1; 35 (7): 405-8.

    AbstractWe report the case of a 74-year-old woman with elevated liver enzyme levels in whom abdominal sonographic examination revealed a diffusely heterogeneous liver parenchyma and multiple hypoechoic subcentimetric splenic nodules. Contrast-enhanced sonography (CEUS) revealed that the splenic focal lesions did not enhance. CT examination revealed a low-density, multinodular pattern both in the liver and in the spleen. Core biopsy of 1 hepatic nodule revealed noncaseating epithelioid cell granuloma, and the patient was diagnosed with systemic sarcoidosis. CEUS has shown to be useful in the diagnosis of focal hepatic lesions, but studies referring to splenic lesions are lacking.(c) 2007 Wiley Periodicals, Inc.

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