• CMAJ · Nov 1998

    Case Reports

    Reversible impairment of renal function associated with enalapril in a diabetic patient.

    • M M Albareda and R Corcoy.
    • Servei d'Endocrinologia, Hospital de Sant Pau, Universitat Autònoma de Barcelona, Spain.
    • CMAJ. 1998 Nov 17; 159 (10): 1279-81.

    AbstractAcute renal failure and hyperkalemia due to angiotensin-converting enzyme inhibitors have been described in diabetic patients with other predisposing conditions. The case reported here involves a patient with type 1 diabetes mellitus, microalbuminuria and normal renal function who was treated with enalapril. Two years after initiation of this therapy, at a time when glycemic control was poor, he presented with symptomatic hyperkalemia and impaired renal function accompanied by hyporeninemic hypoaldosteronism. This case illustrates that reversible impairment of renal function and hyperkalemia can present after 2 years of treatment with angiotensin-converting enzyme inhibitors in patients with precipitating factors.

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