• Hong Kong Med J · Feb 2008

    Predictors of high-dose antipsychotic prescription in psychiatric patients in Hong Kong.

    • Gabriel B K Hung and H K Cheung.
    • Castle Peak Hospital, Tuen Mun, Hong Kong. gabrielhung@hotmail.com
    • Hong Kong Med J. 2008 Feb 1; 14 (1): 35-9.

    ObjectiveTo determine the factors associated with high-dose antipsychotic prescribing for psychiatric patients in Hong Kong.DesignRetrospective cross-sectional study.SettingPsychiatric in-patients and out-patients in the New Territories West Cluster, Hong Kong.PatientsA total of 1129 in-patients and 7520 out-patients who received antipsychotic medications on the study date.Main Outcome MeasuresDemographic and clinical data were compared for patients receiving 'normal' and high dosages of antipsychotic medications.ResultsHigh dosages were prescribed for 104 (9.2%) of the in-patients and 137 (1.8%) of out-patients. Antipsychotic polypharmacy was the most powerful predictor of high-dose prescribing, with an odds ratio of 8.88 for in-patients and 10.82 for out-patients.ConclusionAntipsychotic polypharmacy was the main determinant of high-dose antipsychotic prescribing in this study. Further studies should be conducted to look for other variables contributing to such prescribing in Hong Kong.

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