-
- James J Purtill.
- Department of Orthopedic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
- Instr Course Lect. 2007 Jan 1; 56: 133-7.
AbstractA significant proportion of patients will experience moderate to severe pain after hip or knee replacement surgery. Multimodal pain control regimens have been developed to address this issue. These regimens may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Concern over excessive bleeding in the perioperative period, especially in joint arthroplasty patients receiving anticoagulation therapy, generally prohibits the use of nonspecific NSAIDs. Cyclooxygenase-2 inhibitors, a class of NSAIDs, are not believed to increase the risk of bleeding and may be useful in this population of patients. However, recent research shows increased cardiovascular and renal risks with cyclooxygenase-2 inhibitors and has limited their use for postoperative pain control in joint arthroplasty patients.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..