-
Critical care medicine · May 1988
Dissociation of mean airway pressure and lung volume during high-frequency oscillatory ventilation.
- D W Smith, L R Frankel, and R L Ariagno.
- Department of Pediatrics, Stanford University Medical Center, CA 94305.
- Crit. Care Med. 1988 May 1; 16 (5): 531-5.
AbstractEight kittens were studied during high-frequency oscillatory ventilation (HFOV) using an airway vibrator. HFOV was performed at 1000 and 1800 cycle/min at three present oscillatory amplitude settings and with lungs normal and injured by saline lavage. Change in lung volume (LV) during HFOV was compared to change in LV obtained during static inflation at matched mean airway pressure (Paw) of 5, 10, 15 and 20 cm H2O. LV during HFOV was significantly higher than during static inflation, and increased as oscillatory amplitude increased. LV was significantly lower after lung injury for matched HFOV settings, and was not affected by rate. Dissociation of Paw and LV during HFOV is observed implying that mean alveolar pressure (Palv) exceeds Paw during HFOV in this experimental model. The safe clinical application of HFOV may involve measurement of Palv or LV.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..