• Curr Opin Clin Nutr Metab Care · Nov 2010

    Review

    Do all sedentary activities lead to weight gain: sleep does not.

    • Jean-Philippe Chaput, Lars Klingenberg, and Anders Sjödin.
    • Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark. jepc@life.ku.dk
    • Curr Opin Clin Nutr Metab Care. 2010 Nov 1; 13 (6): 601-7.

    Purpose Of ReviewTo discuss the benefits of having a good night's sleep for body weight stability.Recent FindingsExperimental studies have shown that short-term partial sleep restriction decreases glucose tolerance, increases sympathetic tone, elevates cortisol concentrations, decreases the satiety hormone leptin, increases the appetite-stimulating hormone ghrelin, and increases hunger and appetite. Short sleep duration might increase the risk of becoming obese, because it does not allow the recovery of a hormonal profile facilitating appetite control. Lack of sleep could also lead to weight gain and obesity by increasing the time available for eating and by making the maintenance of a healthy lifestyle more difficult. Furthermore, the increased fatigue and tiredness associated with sleeping too little could lessen one's resolve to follow exercise regimens.SummaryShort sleep duration appears to be a novel and independent risk factor for obesity. With the growing prevalence of chronic sleep restriction, any causal association between reduced sleep and obesity would have substantial importance from a public health standpoint. Future research is needed to determine whether sleep extension in sleep-deprived obese individuals will influence appetite control and/or reduce the amount of body fat.

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