• Arch. Fr. Pediatr. · Mar 1992

    Review

    [Neonatal malignant tumors. Apropos of 75 cases].

    • C Teinturier, C Kalifa, O Hartmann, F Flamant, and J Lemerle.
    • Service d'Oncologie Pédiatrique, Institut Gustave-Roussy, Villejuif.
    • Arch. Fr. Pediatr. 1992 Mar 1; 49 (3): 187-92.

    AbstractFrom 1975 to 1986, 75 neonates were treated at the Institute Gustave-Roussy for a malignant solid tumor, comprising 1.7% of the overall oncopediatric population treated during the same period of time. Of these 75 patients, 47 (62%) presented with neuroblastomas, 15 (20%) with mesenchymal tumors, 9 (12%) with germ cell tumors and 4 with various other types of tumors. Treatment consisted of surgery in 63 patients, chemotherapy in 43 and radiotherapy in 18. The 5 year crude survival rate was 77%. Neuroblastomas did the best with a crude survival rate of 89%. The young age of the patients resulted in two types of problems: immediate tolerance and long term sequelae. The therapeutic regimen should take into account the good prognosis of the majority of these tumors in order to decrease delayed effects.

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