• Am. J. Hematol. · Jan 1979

    Case Reports

    Cold agglutinin autoimmune hemolytic anemia in nonhematologic malignancies.

    • J Wortman, W Rosse, and G Logue.
    • Am. J. Hematol. 1979 Jan 1; 6 (3): 275-83.

    AbstractFour patients with nonhematologic malignancies had the simultaneous finding of hemolytic anemia due to high-titer cold agglutinins. In each patient, the cold agglutinin had "anti-I" specificity and was of the IgM kappa immunoglobulin class. Although patients with hematologic malignancies not uncommonly have cold agglutinins, the association between these antibodies and nonhematologic malignancies is unusual.

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