• Nadine Nakazawa.
• Stanford Hospital & Clinics, Stanford, CA, USA. nnakazawa17@hotmail.com
• Semin Oncol Nurs. 2010 May 1; 26 (2): 121-31.

ObjectiveTo provide a review of the pathogenesis, prevention, and management strategies of infectious and thrombotic complications of central venous access devices (CVADs).Data SourceJournal articles, case reports, product information, personal experience, professional guidelines.ConclusionInfectious and thrombotic catheter-related complications are common and serious complications that can negatively impact patient outcomes. There has been significant national attention on patient safety, and in particular, the prevention of catheter-related bloodstream infections.Implications For Nursing PracticeClinicians have a crucial role in preventing and identifying CVAD-related complications. Understanding the pathogenesis of infectious and thrombotic complications, the principles of best practice, and adhering to these practices consistently, in all practice settings, are critical in order to minimize unnecessary risks to patients with an indwelling CVAD.Copyright 2010 Elsevier Inc. All rights reserved.

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