• Yoshio Shima, Hiroko Ishikawa, Yoshikatsu Matsumura, Kentaro Yashiro, Mizue Nakajima, and Makoto Migita.
• Department of Pediatrics, Nippon Medical School, Tokyo, Japan. shima-p@nms.ac.jp
• Eur. J. Pediatr. 2011 Feb 1; 170 (2): 237-40.

AbstractIdiopathic intrauterine constriction/closure of the ductus arteriosus, which is distinct from that secondary to maternal exposure to non-steroidal anti-inflammatory drugs, such as indomethacin, or structural cardiac defect, is an uncommon event that often results in severe fetal-neonatal morbidity and mortality. We reported a case of idiopathic fetal ductal constriction, in which the diagnosis was confirmed by documentation of an abnormal four-chamber view of the fetal heart at 38 weeks of gestation on obstetric ultrasound examination. A female infant weighing 2,816 g was born by Cesarean section, and her postnatal course was mild; transient tachypnea requiring only several days of supplemental oxygen with spontaneous regression of the abnormal echocardiographic findings by 3 months of age. The incidence of idiopathic constriction/closure of the fetal ductus arteriosus may be underestimated, particularly with a negative history of maternal drug exposure and mild postnatal clinical presentation.

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