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- P Jouvet, P Hubert, D Jan, P Niaudet, A Beringer, C Narcy, M Daudon, M Broyer, and Y Revillon.
- Service de Réanimation Médicochirurgicale Pédiatrique Polyvalente, Hôpital des Enfants-Malades, Paris.
- Arch. Fr. Pediatr. 1991 Nov 1; 48 (9): 637-9.
AbstractHyperoxaluria type I (HPI) is a metabolic disorder secondary to liver alanine glyoxylate aminotransferase deficiency. Renal failure occurs due to the excessive production and precipitation of oxalate in the kidney. Combined liver-renal transplantation is the correct treatment for this condition when end-stage renal failure occurs as with renal transplantation alone the risk of recurrence of the same pathology in the transplanted kidney would be high. We report the case of a 4 year-old child with HPI suffering from terminal renal failure in whom a hepato-renal transplantation was performed: six months later, creatinine clearance was 62 ml/min/1.73 m2 and liver function tests were normal.
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