• Surgical infections · Jan 2006

    Review

    Antimicrobial treatment of sepsis.

    • Paolo Grossi and Daniela Dalla Gasperina.
    • Department of Infectious Diseases, University of Insubria, Varese, Italy. paolo.grossi@uninsubria
    • Surg Infect (Larchmt). 2006 Jan 1; 7 Suppl 2: S87-91.

    BackgroundSepsis is a major cause of morbidity and death in hospitalized patients worldwide and one of the largest current challenges in critical care.MethodReview of the pertinent English-language literature.ResultsTreatment goals conventionally have included maintenance of systemic perfusion and eradication of sources of infection. Initial empiric antimicrobial regimen should be broad enough to cover all likely pathogens, as there is little margin for error in critically ill patients.ConclusionA multidisciplinary team, including the critical care physician, the microbiologist, the infectious disease specialist, the surgeon, and the clinical pharmacologist, is necessary for optimal patient outcome.

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