• Human reproduction · Sep 2008

    Prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment.

    • H Volgsten, A Skoog Svanberg, L Ekselius, O Lundkvist, and I Sundström Poromaa.
    • Department of Women's and Children's Health, Uppsala University Hospital, 751 85 Uppsala, Sweden. helena.volgsten@kbh.uu.se
    • Hum. Reprod. 2008 Sep 1; 23 (9): 2056-63.

    BackgroundThis study was undertaken to determine the prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization (IVF) treatment.MethodsParticipants were 1090 consecutive women and men, 545 couples, attending a fertility clinic in Sweden during a two-year period. The Primary Care Evaluation of Mental Disorders (PRIME-MD), based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edn (DSM-IV), was used as the diagnostic tool for evaluating mood and anxiety disorders.ResultsOverall, 862 (79.1%) subjects filled in the PRIME-MD patient questionnaire. Any psychiatric diagnosis was present in 30.8% of females and in 10.2% of males in the study sample. Any mood disorder was present in 26.2% of females and 9.2% of males. Major depression was the most common mood disorder, prevalent in 10.9% of females and 5.1% of males. Any anxiety disorder was encountered in 14.8% of females and 4.9% males. Only 21% of the subjects with a psychiatric disorder according to DSM-IV received some form of treatment.ConclusionsMood disorders are common in both women and men undergoing IVF treatment. The majority of subjects with a psychiatric disorder were undiagnosed and untreated.

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