• J. Thromb. Thrombolysis · Apr 2004

    Review Case Reports

    Thromboembolism and toxic shock syndrome: a case presentation and literature update.

    • U M Musharrafieh, G W Jamaleddine, A T Taher, W Y Almawi, and Z A Tabbara.
    • Department of Family Medicine, American University of Beirut Medical Center, PO Box 113-8044, Beirut, Lebanon. um00@aub.edu.lb
    • J. Thromb. Thrombolysis. 2004 Apr 1; 17 (2): 133-7.

    AbstractA case of progressive shock and multisystem organ failure is reported for an 18 year old Lebanese woman, clinically diagnosed as toxic shock syndrome (TSS). The patient developed cough and dyspnea during hospitalization; chest CT angiography revealed thromboembolism of the pulmonary artery. CBC analysis showed leukocytosis with a white cell count (WCC) with a marked increase in PT and PTT coupled with reduced protein S, antithrombin III, and protein C levels. The patient improved gradually and was discharged from the hospital 7 days later on oral anticoagulation, and was followed up for six months with no disease recurrence or complications. To our knowledge, this is the first reported case in the literature of toxic shock syndrome associated with pulmonary thromboembolism.

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