• V Wenzel, R S Fuerst, A H Idris, M J Banner, W J Rush, and D J Orban.
• Department of Anesthesiology, University of Florida College of Medicine, Gainesville.
• Ann Emerg Med. 1995 Mar 1; 25 (3): 386-9.

Study ObjectiveTo develop an automatic mechanical device capable of performing active compression-decompression (ACD) CPR in laboratory animals.DesignA swine model was used to study standard and ACD CPR. One-minute periods of standard mechanical chest compressions were alternated with mechanical ACD CPR.SettingUniversity hospital laboratory.InterventionsA commercially available device that provided standard chest compressions only was modified to deliver ACD CPR.ResultsThe absolute difference in intrapleural pressure and tidal volume almost doubled during ACD CPR compared with that with standard CPR.ConclusionThe presence of a greater negative change in intrapleural pressure confirmed that active decompression of the chest had occurred and that the device was capable of performing ACD CPR. The device provides consistent rate, depth, force, and duty cycle.

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