• Neurological research · Sep 1986

    Clinical Trial Controlled Clinical Trial

    Chronic pain treatment with intravenous lidocaine.

    • P Petersen, J Kastrup, I Zeeberg, and G Boysen.
    • Neurol. Res. 1986 Sep 1; 8 (3): 189-90.

    AbstractIn a few uncontrolled studies intravenous lidocaine has been used in the treatment of chronic pain. In a controlled study we used intravenous lidocaine in 18 patients with severe chronic pain states due to various but mainly neurological diseases. After the infusion of lidocaine 14 patients (78%) had significant pain relief ranging from 2 hours to 25 days. There was no significant effect of placebo infusion with isotonic saline. The mechanism of the pain relieving ability of intravenous lidocaine is unknown.

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