• Am. J. Crit. Care · May 2016

    Long-Term Survival after Cardiac Surgery in Patients with Chronic Obstructive Pulmonary Disease.

    • Jimmy T Efird, William Griffin, Wesley T O'Neal, Stephen W Davies, Kristin Y Shiue, Marysia Grzybowski, Linda C Kindell, Alan P Kypson, Mark Bowling, T Bruce Ferguson, Lada Alger, and Patricia B Crane.
    • Jimmy T. Efird is director, Center for Epidemiology and Outcomes Research at the East Carolina Heart Institute, East Carolina University, Greenville, North Carolina. William Griffin is an intern in the Department of Internal Medicine at the Medical University of South Carolina, Charleston, South Carolina. Wesley T. O'Neal is a resident in the Department of Internal Medicine at Wake Forest Baptist Medical Center, Winston-Salem, North Carolina. Stephen W. Davies is a resident in the Department of General Surgery at the University of Virginia Health System, Charlottesville, Virginia. Kristin Y. Shiue is an external research consultant for the Office of Research and Creative Activities, College of Nursing, East Carolina University. Marysia Grzybowski is a cardiovascular epidemiologist and assistant professor in the Department of Public Health, East Carolina University. Linda C. Kindell is a nurse specialist and clinical database manager at the East Carolina Heart Institute, East Carolina University. Alan P. Kypson is chief of the Division of Cardiothoracic Surgery at the East Carolina Heart Institute, East Carolina University. Mark Bowling is associate chief of the Division of Pulmonary and Critical Care Medicine, Vidant Medical Center, Greenville, North Carolina. T. Bruce Ferguson is a professor of cardiothoracic surgery in the Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University. Lada Alger is a clinical research coordinator at Eastern Virginia Medical School, Norfolk, Virginia. Patricia B. Crane is associate dean, Office for Research and Creative Activities, College of Nursing, East Carolina University.
    • Am. J. Crit. Care. 2016 May 1; 25 (3): 266-76.

    BackgroundAlthough many patients with chronic obstructive pulmonary disease (COPD) require a prolonged length of stay (PLOS) following coronary artery bypass grafting (CABG), the impact of PLOS on long-term survival has not been examined in this population.ObjectivesTo determine the association between PLOS and long-term survival among COPD and non-COPD patients after CABG and to examine consequent policy and practice-based implications.MethodsA retrospective cohort study of CABG patients was conducted between 2002 and 2011. Long-term survival was compared in patients with and without COPD and stratified by PLOS. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model.ResultsA total of 203 patients (4.2%) had PLOS after nonemergent CABG (N = 4801). PLOS was an important independent predictor of decreased long-term survival (no COPD, no PLOS: HR = 1.0; COPD, no PLOS: adjusted HR [95% CI], 1.8 [1.5-2.1]; no COPD, PLOS: 3.3 [2.5-4.4]; COPD, PLOS: 6.0 [4.4-8.2]; PTrend < .001).ConclusionsCOPD and PLOS are 2 of many factors that affect long-term mortality in postoperative CABG patients. Aggressive treatment strategies aimed at early weaning off of mechanical ventilation and prevention of reintubation among COPD patients must be considered carefully as a means to reduce length of stay after CABG. Our results also have important implications for the long-term management of these patients and strategies for containing costs over the life course of the patient.©2016 American Association of Critical-Care Nurses.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…