• J Stroke Cerebrovasc Dis · Oct 2013

    Melatonin receptor agonists for treating delirium in elderly patients with acute stroke.

    • Tsuyoshi Ohta, Kenichi Murao, Kosuke Miyake, and Koichiro Takemoto.
    • Department of Neuroendovascular Treatment, Shiroyama Hospital, Osaka, Japan. Electronic address: tsuyoshi@ya2.so-net.ne.jp.
    • J Stroke Cerebrovasc Dis. 2013 Oct 1; 22 (7): 1107-10.

    BackgroundDelirium is considered to worsen life prognosis in elderly patients with stroke. We examined the effects of the melatonin receptor agonist ramelteon for treating delirium in elderly stroke patients with insomnia in comparison to the other drugs.MethodsElderly patients with delirium and insomnia after acute stroke who were treated with ramelteon (7 patients; mean age 76 years) and the other drugs (21 patients; mean age 77.3 years) between July 2011 and March 2012 at our hospital were retrospectively examined.ResultsAll patients treated with ramelteon had a significant improvement within a week and were started on early and aggressive rehabilitation. No patient experienced oversedation, neurologic deterioration, or any other worsening effect associated with ramelteon treatment.ConclusionsMelatonin receptor agonists may be effective for the treatment of delirium in elderly patients with acute stroke.Copyright © 2013 National Stroke Association. Published by Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…