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Ann Thorac Cardiovasc Surg · Oct 2002
Case ReportsMethylene blue administration in severe systemic inflammatory response syndrome (SIRS) after thoracic surgery.
- Martin Friedrich, Anselm Bräuer, Theo Tirilomis, Shahram Lotfi, Frank Mielck, and Thomas Busch.
- Department of Thoracic and Cardiovascular Surgery, Emergency and Intensive Care Medicine, Georg-August University, G ttingen, Germany.
- Ann Thorac Cardiovasc Surg. 2002 Oct 1; 8 (5): 306-10.
AbstractA 66-year-old male patient developed significant pleural effusion on the right side six years after coronary bypass grafting and mitral valve replacement. After pleurocentesis, hemo-pneumothorax developed and finally resulted in complete atelectasis of the right lung. Three weeks later, the patient was transferred to our department, and underwent a right lateral thoracotomy. The hematoma was removed and a complete decortication was performed. Four hours postoperatively the patient developed severe SIRS with beginning multiorgan failure. Even extremely high doses of norepinephrine could not raise the systemic vascular resistance. Single intravenous administration of methylene blue lead to significant and permanent improvement of the hemodynamic status.
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