• J. Am. Coll. Surg. · Jul 2004

    Comparative Study

    Off-pump versus on-pump coronary artery bypass surgery: does the pump influence outcome?

    • Andrew J Berson, J Michael Smith, Scott E Woods, Kimberly A Hasselfeld, and Loren F Hiratzka.
    • Department of Surgery, Good Samaritan Hospital, Cincinnati, OH 45220, USA.
    • J. Am. Coll. Surg. 2004 Jul 1; 199 (1): 102-8.

    BackgroundThis study assessed hospitalization outcome differences for patients undergoing off-pump coronary artery bypass (OPCAB) grafting compared with patients having coronary artery bypass grafting with cardiopulmonary bypass.Study DesignWe conducted a nested case-control study from an 8-year, hospitalization cohort (n = 7,905) in which the data were collected prospectively. Inclusion criteria included a coronary artery bypass graft only and age greater than 18 years. Cases were patients undergoing OPCAB (n = 360) and controls were patients undergoing coronary artery bypass grafting with cardiopulmonary bypass (n = 1,080). Cases were matched to controls 1:3 on five variables: age (+/- 3 years), gender, diabetes, New York Heart Association Functional Classification, and surgical year (+/- 3 years). The 13 outcomes of interest were mortality, length of hospitalization, ICU length of stay, return to ICU, ventilator time, intraoperative complications, pulmonary complications, neurologic complications, renal complications, gastrointestinal complications, sternal wound infections, highest postoperative creatine kinase level, and units of blood products given during the procedure. Using logistic regression we controlled for eight confounding variables.ResultsPatients undergoing OPCAB had a significantly shorter length of hospitalization (relative risk [RR] = 0.95; 95% CI, 0.91-0.99%), fewer pulmonary complications (RR = 0.45; 95% CI, 0.22-0.88%), fewer intraoperative complications (RR = 0.04; 95% CI, 0.0048-0.31%) fewer blood product units given (RR = 0.31; 95% CI, 0.14-0.42%) and lower postoperative creatine kinase (RR = 0.99; 95% CI, 0.98-0.99%). There were no considerable differences for the remaining nine outcomes, including mortality and neurologic complications.ConclusionsPatients undergoing OPCAB had a considerably shorter length of hospitalization, had fewer pulmonary and intraoperative complications, and received a lower volume of blood products.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…