• Curr Cardiol Rev · Aug 2011

    Review

    Sepsis-induced cardiomyopathy.

    • Francisco J Romero-Bermejo, Manuel Ruiz-Bailen, Julian Gil-Cebrian, and Maria J Huertos-Ranchal.
    • Intensive Care Unit, Critical Care and Emergency Department, Puerto Real University Hospital, Cadiz, Spain. romerobermejo@gmail.com
    • Curr Cardiol Rev. 2011 Aug 1; 7 (3): 163-83.

    AbstractMyocardial dysfunction is one of the main predictors of poor outcome in septic patients, with mortality rates next to 70%. During the sepsis-induced myocardial dysfunction, both ventricles can dilate and diminish its ejection fraction, having less response to fluid resuscitation and catecholamines, but typically is assumed to be reversible within 7-10 days. In the last 30 years, It's being subject of substantial research; however no explanation of its etiopathogenesis or effective treatment have been proved yet. The aim of this manuscript is to review on the most relevant aspects of the sepsis-induced myocardial dysfunction, discuss its clinical presentation, pathophysiology, etiopathogenesis, diagnostic tools and therapeutic strategies proposed in recent years.

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