• J Bronchology Interv Pulmonol · Jan 2011

    Pleuroparenchymal fibroelastosis presenting as a hypermetabolic lung nodule.

    • Jenny S Machuca, Masooma Niazi, and Gilda Diaz-Fuentes.
    • Pulmonary and Critical Care Division, Bronx Lebanon Hospital Center affiliated with Albert Einstein of Medicine, NY.
    • J Bronchology Interv Pulmonol. 2011 Jan 1; 18 (1): 65-8.

    AbstractIdiopathic pleuroparenchymal fibroelastosis is a rare, benign entity consisting of fibrotic thickening of the pleura and subpleural parenchyma due to elastic fiber proliferation. We present an elderly, male smoker with chronic obstructive airway disease and bilateral apical pleuropulmonary fibrotic changes. The computed tomogram of the chest showed a spiculated nodule in the left upper lobe and chronic fibrotic nodular changes in the right lung. A positron emission tomographic (PET) scan with 18-fluorodeoxyglucose-PET showed a hypermetabolic nodule in the left upper lobe and uptake by the left axillary lymph nodes. Surgical resection of the nodule for presumptive malignancy showed fibroelastosis with reactive lymph node hyperplasia. To our knowledge, this is the first reported case of nodular parenchymal fibroelastosis, with increased uptake as shown on a PET scan.

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