• Xiaohan Xu, Ying Wang, Jie Zhang, Yingying Du, Yanna Li, Na Xing, Xin Wei, Zhisong Li, Zhongyu Wang, Jinhu Xue, Jie Yan, and Wei Zhang.
• Department of Anesthesiology, The First Affiliated Hospital of Zhengzhou University, Henan, China.
• Transfus Apher Sci. 2015 Aug 1; 53 (1): 48-51.

PurposeIntraoperation autologous blood transfusion is an effective method that is used in surgeries with an important blood loss. Several studies suggest that massive blood transfusion is one of the independent risks for postoperative cognitive dysfunction (POCD). Whether the autologous blood is one of the risk factor for POCD or not, we retrospectively examined the incidence of POCD and the probable risk factors in patients undergoing lumbar surgery in our hospital, with the same aged non-POCD patients as controls.MethodsEighty-one patients who underwent lumbar surgery were included. Perioperative data were examined for association with POCD on the 7 postoperative days by a Mini-Mental State Test. Multivariable logistic regression analysis was conducted to determine the probable risks associated with POCD.ResultsPOCD was found in 21 patients. Participants who developed POCD were more likely to had a lower eduction level, more likely to had more blood loss, higher incidence of preoperative anemia, and perioperative allogeneic blood transfusion of more than 3 units as independent risk factors for POCD 7 d postoperatively (P < 0.05). Otherwise, there is no significant difference of the patients received autologous blood or not (P > 0.05).ConclusionAutologous blood transfusion is not a risk factor for POCD in aged patients following lumbar surgery. Autologous blood is likely to be a better method of intraoperative blood transfusion during lumbar spine surgery.Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

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