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Int. J. Antimicrob. Agents · Oct 2003
Review Comparative StudyShort term therapy for uncomplicated urinary tract infection today. Clinical outcome upholds the theories.
- B Lobel.
- Department of Urology, Hopital Pontchaillou, Rue Henri le Guilloux, F-35033, Rennes, France. bernard.lobel@chu-rennes.fr
- Int. J. Antimicrob. Agents. 2003 Oct 1; 22 Suppl 2: 85-7.
AbstractThe clinical and bacteriological activity of fosfomycin trometamol (FT) has been compared with several other antibiotics in the treatment of uncomplicated urinary tract infections. A single dose of FT had activity comparable with a 5-day course of trimethoprim in a trial where the causative organism and its sensitivity were unknown. In another trial FT showed better long term eradication compared with a 5-day course of cephalexin and other studies suggested a single dose of FT was comparable with a 7-day course of nitrofurantoin or norfloxacin. There were few important side effects with fosfomycin therapy and it was considered a safe and effective first line treatment in uncomplicated urinary tract infection.
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