• Am J Emerg Med · Aug 2016

    Electrocardiography changes in acute aortic dissection-association with troponin leak, coronary anatomy, and prognosis.

    • Leili Pourafkari, Arezou Tajlil, Samad Ghaffari, Mohammadreza Chavoshi, Kasra Kolahdouzan, Rezayat Parvizi, Raziyeh Parizad, and Nader D Nader.
    • Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Anesthesiology, University at Buffalo, Buffalo, NY 14214. Electronic address: leili.p@gmail.com.
    • Am J Emerg Med. 2016 Aug 1; 34 (8): 143114361431-6.

    BackgroundElectrocardiography (ECG) offers some information that may be used to prognosticate acute type A aortic dissection (AAOD) for short- and long-term mortality.MethodsWe retrospectively analyzed the electrocardiograms of patients with AAOD admitted from March 2004 to March 2015. The frequency of ECG findings and their prognostic value on hospital and follow-up mortality were investigated. Findings pertaining to coronary involvement and troponin level were also examined.ResultsA total of 120 men and 64 women were admitted. Acute ischemic changes were reported in 38.0%, whereas T inversion was the most common recorded abnormality, which occurred in 38.6%. Acute ST-elevation myocardial infarction was detected in 16.3%. Troponin increased in 36.6%; 21.9% of the patients underwent coronary angiography among which 70% were normal. Coronary involvement or troponin increase was not different in patients with acute ECG changes. During hospitalization, 45.7% of the patients died. In multivariate analyses, ST elevation in lead aVR was associated with higher hospital death (odds ratio, 5.30; 95% confidence interval, 1.09-25.73; P = .038), whereas QRS greater than 120 milliseconds was associated with long-term mortality (hazard ratio, 2.45; 95% confidence interval, 1.25-3.76; P = .006).ConclusionAcute ischemic ECG changes are common in AAOD, and a completely normal ECG is infrequently encountered. Acute ECG changes were not associated with the increased troponin or the presence of coronary lesions in angiography.Published by Elsevier Inc.

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