• P Touza Pol, C Rey Galán, J A Medina Villanueva, P Martinez-Camblor, J López-Herce, and en representación del Grupo de Estudio del Fallo Renal Agudo de la Sociedad Española de Cuidados Intensivos Pediátricos.
• Unidad de Cuidados Intensivos Pediátricos, Hospital Madrid Torrelodones, Torrelodones, Madrid, España. Electronic address: tousrula@yahoo.es.
• An Pediatr (Barc). 2015 Dec 1; 83 (6): 367-75.

IntroductionAcute kidney injury (AKI) is a severe complication in critically ill children. The aim of the study was to describe the characteristics of AKI, as well as to analyse the prognostic factors for mortality and renal replacement therapy (RRT) in children admitted to Paediatric Intensive Care Units (PICUs) in Spain.Patients And MethodsProspective observational multicentre study including children from 7 days to 16 years old who were admitted to a PICU. A univariate and multivariate logistic regression analysis of the risk factors for mortality and renal replacement therapy at PICU discharge were performed.ResultsA total of 139 cases of AKI were analysed. RRT was necessary in 60.1% of cases. Mortality rate was 32.6%. At PICU discharge RRT was necessary in 15% of survivors. Thrombopenia and low creatinine clearance values were prognostic markers of RRT at PICU discharge. High values of platelets, serum creatinine and weight were associated with higher survival.ConclusionsCritically ill children with AKI had a high mortality and morbidity rate. Platelet values and creatinine clearance are markers of RRT at PICU discharge, whereas number of platelets, serum creatinine and weight were associated with mortality.Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.

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