• Expert Rev Anti Infect Ther · Jan 2015

    Review Meta Analysis

    Risk factors for lung infection in stroke patients: a meta-analysis of observational studies.

    • Mei-zhen Yuan, Feng Li, Xin Tian, Wei Wang, Man Jia, Xue-feng Wang, and Guang-wei Liu.
    • a 1 Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
    • Expert Rev Anti Infect Ther. 2015 Jan 1; 13 (10): 1289-98.

    BackgroundThe aims of this meta-analysis were to evaluate the risk factors associated with lung infections in stroke patients and to provide evidence for prevention decisions.MethodsWe searched the Embase, PubMed, EBSCO and Web of Science databases to collect studies from January 2000 to July 2015.ResultsThe meta-analysis identified 23 risk factors for lung infections in stroke patients, and the top 5, ranked by order according to odds ratio values (95% confidence interval), were as follows: multiple vertebrobasilar stroke, 22.99 (4.04, 130.83); National Institutes of Health Stroke Scale score >15 points, 14.63 (8.54, 25.08); mechanical ventilation, 10.20 (7.15, 14.57); nasogastric tube use, 9.87 (6.21, 15.70); and dysphagia, 7.50 (2.60, 21.65).ConclusionPreventive measures should be taken against these risk factors to reduce the incidence of lung infection.

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