• Psychiatr Neurol Med Psychol (Leipz) · Nov 1984

    [Clinical and cisternographic differential diagnosis between presenile dementia and Hakim syndrome].

    • J Kulczycki and T Jedrzejczak.
    • Psychiatr Neurol Med Psychol (Leipz). 1984 Nov 1; 36 (11): 674-7.

    AbstractThe authors compared with regard clinical and the radionuclide cisternography examination 27 patients with Hakim-Syndrome and 11 with Alzheimer-Disease. In all cases, dementia was a stable symptom. Patients with Hakim-Syndrome have an early gait disturbance, ataxia and epileptic seizures. Only in case of patients with Alzheimer-Disease we found aphasia, apraxia and psychotic disorders. 24 hours after the injection radionuclide cisternography showed ventricular retention and absence of parasagital accumulation only in patients with Hakim-Syndrome. Lighter changes (mixed cisternographic pattern) were found in patients with Alzheimer-Disease as well.

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