• YuPeng Wang, Ping Wang, and HongWei Li.
• Department of Heart Center, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China.
• Clin Cardiol. 2010 Feb 1; 33 (2): 72-6.

BackgroundIt is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high-density lipoprotein cholesterol.HypothesisPulmonary embolism has a negative correlation with the level of high-density lipoprotein cholesterol.MethodsA total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non-trunk embolism in group B.ResultsThe results showed that the level of high-density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non-trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high-density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C-reactive protein.ConclusionsPulmonary arterial trunk embolism is negatively correlated with the level of high-density lipoprotein cholesterol.Copyright 2010 Wiley Periodicals, Inc.

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