• Eur. J. Pediatr. · Mar 2000

    Case Reports

    Procalcitonin may help differentiate disseminated herpes simplex viral infection from bacterial sepsis in neonates.

    • M Hatherill, K Sykes, A G McIntyre, and I A Murdoch.
    • Paediatric Intensive Care Unit, Guy's Hospital, St. Thomas' Street, London SE1 9RT, UK.
    • Eur. J. Pediatr. 2000 Mar 1; 159 (3): 168-9.

    UnlabelledDisseminated herpes simplex virus infection is a potentially fatal condition which may be difficult to differentiate from bacterial sepsis. We report the case of a neonate with overwhelming herpes simplex (type 2) viraemia who presented with 'septic shock'.ConclusionA low procalcitonin level (1.6 ng/ml), inconsistent with bacteraemia, suggests an alternative aetiology and may strengthen the case for antiviral therapy.

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