• Neuroimaging Clin. N. Am. · May 2016

    Review

    Neuroscience of Tinnitus.

    • Daniel Ryan and Carol A Bauer.
    • Department of Diagnostic Radiology, Southern Illinois University School of Medicine, Memorial Medical Center, 701 North 1st Street, Springfield, IL 62794-9662, USA.
    • Neuroimaging Clin. N. Am. 2016 May 1; 26 (2): 187-96.

    AbstractTinnitus is a consequence of changes in auditory and nonauditory neural networks following damage to the cochlea. Homeostatic compensatory mechanisms occur after hearing loss and these mechanisms alter the balance of excitatory and inhibitory neurotransmitters. In many individuals with hearing loss, chronic tinnitus and related phenomena emerge. Some people with tinnitus are disturbed by this subjective sensation. When auditory network dysfunction is coupled with limbic-gating dysfunction, an otherwise meaningless auditory percept such as tinnitus may acquire negative emotional features. The development of effective treatment options is enhanced by the understanding of the neural networks underpinning tinnitus.Copyright © 2016 Elsevier Inc. All rights reserved.

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