• Med Clin Barcelona · Dec 2014

    Randomized Controlled Trial Comparative Study

    [Tranexamic acid gel in patients treated with oral anticoagulants].

    • Jorge Ripollés-de Ramón, Marta Muñoz-Corcuera, Carmen Bravo-Llatas, and Antonio Bascones-Martínez.
    • Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España. Electronic address: jorgeripolles@hotmail.com.
    • Med Clin Barcelona. 2014 Dec 9; 143 (11): 484-8.

    Background And ObjectivePatients treated with oral anticoagulants have increased susceptibility to bleeding, and therefore any surgical medical procedure and especially oral surgery requires a therapeutic approach that minimizes bleeding effects in these patients.Material And MethodThe working hypothesis was based on studies of local application of tranexamic acid after maxillofacial interventions as effective therapeutic alternative for the prevention and control of bleeding. The aim was to assess the effectiveness of the application of a gel solution tranexamic acid after tooth extraction in anticoagulated patients in terms of healing time and degree of healing.ResultsThe results indicate that application of tranexamic acid gel is very effective for consistency and maintenance in the place of action and shows its efficacy as a procoagulant material.ConclusionsThe application of a gel solution of tranexamic acid in oral anticoagulants patients ameliorates healing time and the bleeding time within the first 48-72 h.Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

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