• Barbara Bruno, Cristiana Maurella, Sara Falco, Alberto Tarducci, Renato Zanatta, Antonio D'Angelo, and Antonio Borrelli.
• Department of Veterinary Science, Clinical Medicine Section, via Leonardo da Vinci 44, 10095, Grugliasco (TO), Italy.
• J Vet Emerg Crit Care (San Antonio). 2015 Jul 1; 25 (4): 502-11.

ObjectiveEvaluation of hemostasis using thromboelastometry in dogs with leishmaniasis before and after treatment.DesignLongitudinal observational study.SettingUniversity veterinary teaching hospital.AnimalsEighty-four adult, client-owned dogs.Measurements And Main ResultsWhole blood samples for the coagulation profile were collected from symptomatic dogs with leishmaniasis (group S), asymptomatic dogs with leishmaniasis after treatment (group T), and a control group of healthy dogs (group H). Hemostasis was evaluated by means of standard coagulation profile (prothrombin time, activated partial thromboplastin time, and fibrinogen) and by thromboelastometry (ROTEM). Prothrombin time and activated partial thromboplastin time were within the upper reference range in all 3 groups. Comparison of the ROTEM variables between the 3 groups showed statistically significant differences between group S versus groups T and H, but remaining within the reference ranges. Statistically significant differences in hematocrit and fibrinogen concentrations were noted between groups (group S vs. H: hematocrit P = 0.001, fibrinogen P = 0.002; Group S vs. T: hematocrit P = 0.001, fibrinogen P = 0.001). These variations have interfered with some parameters of the ROTEM profile.ConclusionsThis study showed normal standard coagulation profiles in all 3 groups evaluated. The ROTEM results did not fall outside of the maximum values of the reference ranges.© Veterinary Emergency and Critical Care Society 2015.

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