• E O'Loughlin, M Ward, A Crossley, R Hughes, A P Bremner, and T Corcoran.
• Department of Anaesthesia, Fremantle Hospital, Perth, Western Australia, Australia; School of Medicine and Pharmacology, Perth, Western Australia, Australia.
• Anaesthesia. 2015 Feb 1;70(2):142-9.

AbstractIt is important to detect and treat hypovolaemia; however, detection is particularly challenging in the conscious, spontaneously breathing patient. Eight healthy male volunteers were monitored using four minimally invasive monitors: Vigileo FloTrac(™) ; LiDCOrapid(™) ; USCOM 1A; and CardioQ(™) oesophageal Doppler. Monitor output and clinical signs were recorded during incremental venesection of 2.5% estimated blood volume aliquots to a total of 20% blood volume removed. A statistically significant difference from baseline stroke volume was detected after 2.5% blood loss using the LiDCO (p = 0.007), 7.5% blood loss using the USCOM (p = 0.019), and 12.5% blood loss using the CardioQ (p = 0.046) and the FloTrac (p = 0.028). Receiver operator characteristic curves for predicting > 10% blood loss had areas under the curve of 0.68-0.82. The minimally invasive cardiac output devices tested can detect blood loss by a reduction in stroke volume in awake volunteers, and may have a role in guiding fluid replacement in conscious patients with suspected hypovolaemia.© 2014 The Association of Anaesthetists of Great Britain and Ireland.

30 keywords...

hide…