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Nihon Kyobu Shikkan Gakkai Zasshi · Apr 1997
Case Reports[Large-cell carcinoma presenting as diffuse thickening of the pleura and resembling malignant mesothelioma].
- H Nakamura, I Ikeda, H Nakahama, O Kitada, and M Sugita.
- Fifth Department of Internal Medicine, Hyogo College of Medicine, Japan.
- Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Apr 1; 35 (4): 451-4.
AbstractA 65-year-old man had a right-sided pleural effusion. A thoracic CT scan revealed diffuse pleural thickening resembling malignant mesothelioma. Repeated needle biopsies did not yield a definitive diagnosis. At autopsy, diffuse pleural thickening was found, and examination of a specimen of lung tissue showed large-cell carcinoma. Hyalinized fibrous tissue with malignant cell infiltration was seen in the thickened pleural tissue and metastatic pleuritis was diagnosed. Large-cell carcinoma of the lung should be considered in the differential diagnosis of pleural thickening.
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