• J. Child Neurol. · May 2001

    Case Reports

    Clonidine treatment increases tics in patients with Tourette syndrome: case report.

    • A R Kessler.
    • Clinic for Applied Neuropsychology, Rehovot, Israel. kesslerb@netvision.net.il
    • J. Child Neurol. 2001 May 1; 16 (5): 380-1.

    AbstractClonidine usually serves as a tic-suppressing agent in patients with Tourette syndrome. A case study is presented in which clonidine at subclinical concentrations led to an exacerbation of the tics and caused severe systemic heat sensations. Involvement of functional abnormalities of the hypothalamus in Tourette syndrome is hypothesized.

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